ACCT 210 Lecture Notes - Lecture 76: Macrophage, Envelope Glycoprotein Gp120, Myositis
12 Jul 2020
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Document Summary
Aids statistics, molecular biology: life cycle of hiv targets for therapy. Problems associated with therapy: new therapeutic options. Viruses: a non-cellular microorganism that can only replicate within cells. Many viruses (e. g. influenza and many animal viruses) have viral envelopes covering their protective protein capsids. The envelopes typically are derived from portions of the host cell membranes (phospholipids and proteins), but include some viral glycoproteins. Functionally, viral envelopes are used to help viruses enter host cells. Glycoproteins on the surface of the envelope serve to identify and bind to receptor sites on the host"s membrane. The viral envelope then fuses with the host"s membrane, allowing the capsid and viral genome to enter and infect the host. Usually, the cell from which the virus itself buds will often die or be weakened, and shed more viral particles for an extended period. Enveloped viruses possess great adaptability and can change in a short time in order to evade the immune system.
