BIOL 001 Lecture Notes - Lecture 19: Blood Vessel, Cyclic Adenosine Monophosphate, Smooth Muscle Tissue

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Blood o2 content goes up > blood vessel lining releases no. > vasodilation (opening blood vessels wider > get more blood flow to that surrounding tissue) Polypeptides tend to be hundreds of amino acids. Insulin 2 polypeptides, joined with disulfide bonds. Amines synthesized from single amino acids, Epinephrine, can be made quickly, dont have to be folded, short term. Solubility affects response pathway different for two types. Short version: signal goes from outside of the target cell to the inside of the target cell, several signaling molecules involved. Pathway water soluble (fig 45. 5 and fig 45. 6) Hormone is secreted via exocytosis (into the surrounding env) Binds to the receptor on the surface of the target cell. Receptor is often a g protein-coupled receptor complex binds to g protein in the membrane. G protein (1st messenger) is then activated. Many kind of kinases their main jobs are to phosphorolate. All act by adding a phosphate group to a specific protein.

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