BIOL 031 Lecture Notes - Lecture 14: Posterior Grey Column, Afferent Nerve Fiber, Motion Sickness

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Discuss the pros and cons of the redundancy of information used to determine proprioception and kinesthesia damaged or not active. Pros: multiple systems can keep balance and posture even if one system is. Cons: can lead to conflicts with other senses leading to ill effects (like sea. Describe pathway by which pain & temperature information travels to the cortex, sickness) including: nature of primary afferents (size, myelination), location of decussation, and area of termination. Nociceptors can respond to multimodal stimuli, if stimuli is potentially harmful. Frequent stimuli include; h+, histamine, cytokines, prostaglandins, and others. Pain information travels in the anterolateral pathway. Ion channels in neurons that open within a certain temperature range known as transient receptor proteins (trp proteins) Afferent axons are small and unmyelinated (no need for rapid communication to cns) Temperature information travels in the anterolateral pathway. Secondary afferent desiccates (crosses) immediately in spinal cord then synapses on tertiary afferent in thalamus.

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