BIOL 031 Lecture Notes - Lecture 18: Macrophage, Motor Neuron, Acetylcholinesterase
18 Sep 2020
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Document Summary
Ach binds to the muscarinic receptor and then is broken down in the synapse by acetylcholinesterase. Choline is then taken back into the axon and can be reused. This causes it to be released from varicosity. Ne then diffuses to the nearby adrenergic (alpha and beta) receptor. Activity then stops as ne gets transported back into varicosity. Ne can be repackaged in the axon or can be broken down my mao in the axon. The structure of the autonomic synapse differs from the model synapse. Autonomic post ganglionic axons end with a series of swollen areas at their distal ends, like beads spaced out on a string. Each of these swellings is known as a varicosity and contains vesicles filled with nt. These branched ends of the axon lie across the surface of the target tissue, but the target does not have clusters of receptors but rather they are random. The somatic motor neuron synapses with the muscle (neuromuscular junction)
