BIOL 031 Lecture Notes - Lecture 6: Glutamine, Epithelium, Oncotic Pressure

• School: College of The Sequoias
• Department: Biology (BIOL)
• Course: BIOL 031
• Professor: carey

Document Summary

Understand basic concepts related to solute transport across epithelial membranes. The cells lining the various tubular segments form layers that are only a single cell thick (monolayers) connected to each other by tight junctions that separate the lumen of the tubule from the interstitial spaces that surround it. The apical or luminal membrane faces the tubular lumen. There are different integral membrane proteins and lipids on each of these surfaces, which means the cells are polarized. Cellular transport: the movement of fluid and solutes sequentially across the apical and basolateral cell membranes (or vice versa) mediated by transporters, channels, and pumps. Paracellular transport: movement of fluid and solutes through the narrow passageway between cells. Tight epithelia: have more occluded tight junctions. Describe the structure and function of the proximal tubule. The proximal tubule is an example of leaky (low resistance) epithelia. S1 is highly convoluted and is the earliest part.