BIOL 031 Lecture Notes - Lecture 11: Proximal Tubule, Diuretic, Electrochemical Gradient
22 Dec 2020
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Describe the distribution of k+ within the body compartments. 98% of k is intracellular: 150 meq/l concentration. Can you think of another reason why this makes sense? (hint: we talked about it above) Describe the mechanisms of k+ transport by the various segments of the nephron and how do they determine the amount of k+ that needs to be excreted in the urine. 67% reabsorbed in the proximal tubule, 20% in the loh - reabsorption is a constant fraction of the amount filtered. Hyperkalemia >5 meq/l (or 5. 5 in some other sources) Explain how the body handles the dietary k+ load. Extracellular fluid 65 meq and tissue stores 3435 meq exchange potassium. Use of insulin, epinephrine, and aldosterone modifies k movement. 90-95 meq to be excreted in the urine. State the hormones and factors that regulate the transfer of k+ into the cell compartment. Insulin - stimulates k+ uptake into the cells. Becauses k uptake into cells (major): predominates.
