NUTR 132 Lecture Notes - Lecture 6: Coeliac Disease, Portal Vein, Gluten
6 Dec 2018
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Protein digestion and absorption i, digestion of protein in the small intestine i. ii. iii. iv. Pancreatic enzymes: trypsin, among others, into the duodenum. Small peptides and amino acids: ready for absorption, protein absorption i. Digestion and absorption takes place: at microvilli surface, within absorptive cells lining small intestine ii. Absorption: active absorption, many different amino acid transport mechanisms, amino acids are sent to the liver via portal vein, gluten sensitivity - celiac disease i. ii. Gluten: protein found in certain grains (wheat, rye, barley) Incomplete gluten breakdown in small intestine leaving small peptides and amino acids iii. Inflammatory response to small peptides and amino acids. 1: autoimmune response, genetic predisposition, functions of proteins i. ii. iii. iv. v. vi. vii. viii. Contributing to satiety: producing vital body structures i. During any day, an adult degrades and makes about 250 grams of protein. Amino acids can be recycled: protein contributes to acid-base balance i. ii. iii. iv.
