NUTR 132 Lecture Notes - Lecture 7: Hyperlipidemia, Abdominal Obesity, Insulin Resistance

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Estimating body fat content & diagnosing obesity, medical experts use percent body fat rather than body weight, acceptable amount of body fat, women 16% to 30%, men 11% to 20%. Obesity based on body fat: women over 35%, men over 25%. ii, body fat distribution & obesity i. ii. iii. Upper-body, android obesity: apple shape , abdominal, visceral, or central obesity, associated with insulin resistance and fatty liver, leads to obesity-related chronic diseases such as cancer, type 2 diabetes, hypertension, high blood lipids, and heart disease. Abdominal fat is released into the liver and promotes inflammation: testosterone and excessive alcohol increase risk. Definition: waist circumference >40 for men, waist circumference >35 for women. iv. Identical twins: similar weights even if raised apart. Genes: affect metabolic rate, fuel use, brain chemistry, and body shape, may account for up to 70% of weight differences. iii. Thrifty metabolism gene: more fat stored to protect against famine, set-point for weight i.

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