NUTR 132 Lecture Notes - Lecture 8: Thiamine Pyrophosphate, Angular Cheilitis, Glutathione Peroxidase

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Thiamin: functions, first b vitamin discovered, helps release energy from carbohydrate, coenzyme form, thiamin pyrophosphate (t p p), participates in reactions d. in which carbon dioxide (c o 2 ) is released. Important in a t p-producing energy pathways involving breakdown of carbohydrates and certain amino acids: thiamin deficiency, disease: , symptoms: Beriberi: weakness. ii. iii. iv. v. vi. vii. viii. Inflammation of the mouth and tongue. a: cracking on tongue and corners of mouth (cheilosis), dermatitis, eye disorders, sensitivity to sun, confusion, occur jointly with niacin, thiamin, and vitamin b-6 deficiencies. i. Angular cheilitis, also called cheilosis or angular stomatitis, causes painful cracks at the corners of the mouth. h: niacin: functions, functions as nicotinic acid or nicotinamide, coenzyme form used in many cellular pathways. i. Involved in 200+ reactions: generating energy (atp) from carbohydrates and fat requires niacin coenzymes. i. ii. Nicotinamide dinucleotide phosphate (nadp: fatty acid synthesis requires niacin coenzyme. i.

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