EBIO 1210 Lecture 16: Patterns of Inheritance & Chromosomal Disorders
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lE C TURE16:06.28 . 18 16
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CHROMOSOMES
Pedigree
:family the that describes immolation ships of parents &children across
generations
man marriagemating
femme offspring
sex not specified 7
patterns of
.
inheritance :
-
Recessively inherited Disorder :
.tends to skip generations
•can be passed from 2unaffected parents (Rr +Rr = w )
-
Dominantly
inherited
Disorder :
•Affected offspring must have affected parent
•Tends to appear every generation
Z
-X-hinted Recessive inherited Disorder :
•More males lgenually effected )
•tends to strip generation
•Never passed from father To son
-Y-tinted inherited Disorders :I
•
only males affected
•passed lather to son automatically
•Y -chromosomes are small ,low mutations fit
I
Rewiring Genetic Disorders :
-
why do mutations that cause genetic disorders survive in population ?
.reintroduction by new mutation
•recessive alleles are masked in heterozygous
•
Heterozygote may have an advantage in certain environments
•Example :sickle an anemia
Document Summary
Pedigree family the that describes immolation ships of parents & children across generations man femme marriagemating offspring sex not specified. 2 from passed inheriteddisorder parent offspring parents affected unaffected must have. More males lgenually effected ) tends to strip generation: never passed from father. Disorders males only passed lather affected to son. Y - chromosomes are automatically low small mutations fit. Disorders why do mutations that cause genetic disorders survive in population reintroduction by new mutation recessive alleles are masked in heterozygous. Heterozygote may have an advantage in certain environments. Mva be caused may by unequal crossovers in prophase. Removes chromosomal segment disorders chat causes or lethal. Unvefcdon : chromosome chromosome becomes from cerebral another some. No nmsjwutwn : between pieces in exchanged www. mn translocation tnttnenw. Meiosis results in one gamete reveres two same type of chromosome another venues no copy. An euprmtm : improper chromosome numbers due to feminization of gunner that had nondignnuion.