MCDB 1150 Lecture Notes - Lecture 25: Electrochemical Gradient, Glut1, Glucose Transporter
17 Nov 2016
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Osmosis same thing as diffusion, but only talking about water moving through a membrane, not solute. Membrane transport box most helpful info will be found on overheads, memorize. Diffusion through a port or a channel is just simple diffusion. Ions and small polar molecules because they aren"t very soluble in the hydrocarbon phase of the membrane. Shape changes in response to a signal. Facilitated diffusion book calls it something else! (form of passive transport?) Has to have a protein carrier physical transfer solute across the membrane. The binding site of glut-1 flips from side to side of the membrane. Gradients are a source of potential energy for cell processes. Entropy gradient is ordered (thus high potential energy) Takes energy to make a gradient because of entropy change (increase in order/decrease in entropy) Energy in gradient can be harnessed to drive energetically unfavorable events in cells. Na+, ca2+, cl- are higher concentration outside and k higher inside cell (concentration gradient)
