MCDB 1150 Lecture Notes - Lecture 23: Integral Membrane Protein, Cell Surface Receptor, Transmembrane Protein

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Of sugars covalently bound to extracellular domain (cid:1445)glycoprotein(cid:1446) Suggested reading: freeman, chapter 6, section 6. 4, pages 132-138. Permeability of the membrane to molecules (membranes are selectively permeable) Rates of movements of molecules across the membrane. Selective permeability different kinds of molecules cross bilayer at very different rates (cm/s) Does not depend on fatty acid tails, cholesterol. Clicker question: selective permeability is determined by the fatty acid composition of the phospholipids and cholesterol content of the membrane. False it depends on the chemical properties of molecules and protein in the membrane. Not water because it"s facilitated by channels and the large polar molecule (carbohydrate) needs a carrier. Effect of size of polar molecules on their diffusion through a pure lipid bilayer (lipids, no protein) Clicker question the black balls represent a solution of like molecules. C) arrows pointing in all directions because diffusion is random. Clicker question the black balls represent two different populations of molecules in solution.

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