BIOL 22000 Lecture Notes - Lecture 13: Active Transport, Pulmonary Circulation, Neuromuscular Junction
26 Jun 2018
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A Heart Pump
oSmaller animals use the contraction of muscles into the body to pump circulatory
fluid
oMost larger animals have heart
oHeart evolved from section of vessels
oHearts develop from tubes
oAdvantages:
Faster circulation
Higher pressure
Increase exchange
Larger body size
Cell can be further away because heart can pump
Cardiac Muscle: Pressure
oValves separate compartments of heart and major vessel
oIs valve is close, Pressure Chamber 1 does not equal to Pressure Chamber 2
oIf a valve is open, pressures will equilibrate
oContraction of cardiac muscle (myocardium) increases pressure within
compartments
oRelaxation of muscle or opening valve can decease pressure
Cardiac Muscle: structure
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o
oIntercalated disk transfer force from cell to cell
To develop large amount force
oGap junction transfer depolarization between cells in a syncitium
oNo neuromuscular junction; action potential starts in cardiac conduction system
So, there is no release Ach, synapse
No neuro stimulus needed
Cardiac muscle is spontaneous depolarized and spread throughout the
muscle
find more resources at oneclass.com
find more resources at oneclass.com
Document Summary
A heart pump: smaller animals use the contraction of muscles into the body to pump circulatory fluid, most larger animals have heart, heart evolved from section of vessels, hearts develop from tubes, advantages: Cell can be further away because heart can pump. Cardiac muscle: structure o: intercalated disk transfer force from cell to cell. To develop large amount force: gap junction transfer depolarization between cells in a syncitium, no neuromuscular junction; action potential starts in cardiac conduction system. So, there is no release ach, synapse. Cardiac muscle is spontaneous depolarized and spread throughout the muscle o o. We have two sources of calcium here; looking at 2 and 3, calcium that is coming in acts as a ligand to open the channel for the calcium in sr to be released. Ncx moves calcium out and moves sodium in, this is secondary active transport and no atp needed.
