BIOSC-101 Lecture Notes - Lecture 4: Radiant Energy, Chemical Kinetics, Kinetic Energy

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Large macromolecules can have multiple ligand binding sites. Binding reactions can be independent or alter the binding affinity of another molecule at a distant site. Dissociation of water molecules breaks one of the o-h bonds. Ph: negative log of the hydrogen ion concentration in solution. Acid: any molecule that tends to release a hydrogen ion (h+) Base: any molecule that readily combines with a hydrogen ion. Buffers: weak bases and acids that bind to excess h+ or oh- to maintain a constant ph in the cytoplasm. The buffering capacity depends on the concentration of the buffer and the relationship between its pka value and the ph. Titration: slow addition of one solution (with known concentration) to another solution (with known volume) to determine its concentration. Acid-base titrations are monitored by the change of ph. Principal forms of energy: kinetic or potential. Thermal energy: energy of the motion of molecules. Mechanical energy: energy of movement within cells.

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