BIOSC-139 Lecture Notes - Lecture 14: Golgi Apparatus, Ribosomal Rna, Lysosome
Document Summary
Biosc-139: allows specific endocytosis and transcytosis, cells use to concentrate materials in limited supply, clathrin-coated pits provide main route for endocytosis and transcytosis, uptake of enzymes, low-density lipoproteins, iron, insulin, and, unfortunately, viruses, diphtheria, and cholera toxins. Receptor-mediated endocytosis: different coat proteins, caveolae, capture specific molecules (folic acid, tetanus toxin) and use transcytosis, involved in cell signaling but exact function unknown, coatomer, function in vesicular trafficking. Selective diffusion establishes rmp: electrochemical gradient established, k+ diffuses out of cell through k+ leakage channels, proteins cannot inside cell. Mitochondria: double-membrane structure with inner shelflike cristae, provide most of cell"s atp via aerobic cellular respiration, requires oxygen, contain their own dna, rna, ribosomes, similar to bacteria; capable of cell division called fission. Endoplasmic reticulum (er: interconnected tubes and parallel membranes enclosing cisterns, continuous with outer nuclear membrane, two varieties, rough er, smooth er.