PSYCH 14 Lecture Notes - Lecture 25: Monoamine Oxidase Inhibitor, Tricyclic Antidepressant, Transcranial Magnetic Stimulation
Document Summary
50 percent receive benefit--> no difference in effectiveness of all 4. Ssri"s most common *****- block the presynaptic reuptake of serotonin. Mixed reuptake inhibitors- venlafaxine (effexor) netazodone (serzone) Mao- block enzyme mao that breaks down such neurotransmitters as norepenephrine and serotonin. Used less because of eating and drinking foods and beverages containing tyramine* Tricyclic ad"s used the most before ssri"s. Desensitize/down regulate neurophrine (and serotonin is affected) Tricyclics lethal if taken in excessive doses. Caution with patients who have suicidal tendencies. More important goal then recovery: delay the next depressive episode or even prevent it entirely. Drug treatment should go well beyond the termination of a depressive episode (6-12 months after) Gradually withdraw from drug over weeks or months* Lithium carbonate: common salt widely available in the natural environment. Dosage has to be carefully regulated to prevent toxicity (poisoning) Also preventive in treating and preventing manic episodes.
