BIOL 141 Lecture Notes - Lecture 4: Sickle-Cell Disease, Alpha Helix, Hydrolysis
Document Summary
Fatty acids + glycerol + phospholipid (+, hydrophobic) Typically come from animals, single bonds (one linear piece) At least one fatty acid tail w/ double bond, kinks are locked that way, becomes more fluid as double bonds cause bending. Soap: glycerol w/ fatty acid tail and polar head group. Shape wise is different: rings, not a linear structure. Hydrocarbons: dislike water, don"t look like a fatty acid. Cholesterol: important for maintaining membrane fluidity/ protein raft. Peptide bonds: not polar, but chain: polar to an extent. Side chains: direct what secondary structure is made, but don"t participate directly in bonding. Disulfide bridge: cystines, makes your hair curly, don"t change w/ heat or ph. Quaternary structure: 2+ polypeptides, chains form dne macromolecule. Sickle cell anemia: changing dne primary structure messes things up. Beta subunit: changed in such a way that hemoglobins aggragate w/ one another.
