BIOL 141 Lecture Notes - Lecture 1: Stromatolite, Central Dogma Of Molecular Biology, Cell Theory
Monday, August 28, 2017
BIOL 141
ā¢Go through the syllabus - quiz"
ā¢Characteristics of life: response to stimuli, reproduction, DNA, heritage, nutrients,
organization (cells, atoms etc), birth/death, homeostasis"
-Energy, cells, information, replication, evolution"
ā¢Viruses - alive: genome, evolve, they use the energy of the host cell and replicate
their genome, has a ālife cycleā"
Not alive: not cells"
ā¢Ebola: virus, large outbreaks in western Africa, promising vaccine since 2016, has
two diļ¬erent shapes - makes it easy to miss a cure"
ā¢Fundamental rules of biology: cell theory, central dogma (DNA, RNA, etc), structure
and function, evolution (allows the diversity of life)"
ā¢Homologous proteins all share a common ancestor - conserved structures indicate
similar function"
ā¢Homology: common evolutionary ancestor"
ā¢Phylogeny: study similarities to infer evolution, sequence comparisons"
ā¢
ā¢Central Dogma: Flow of information from nucleic acids to protein expression of
function"
ā¢āGenotype is transferred between generation, expression of proteins determines
phenotype`"
ā¢Genes are reading āparticular chaptersā in the DNA"
ā¢Cell is the smallest unit we can consider āaliveā"
ā¢Natural selection pressures cause changes in populations over time"
ā¢Mutations lead to individual variation"
ā¢ONLY POPULATIONS EVOLVE! - changes in the variation frequency in a population
leads to evolution."
ā¢Evidence of ļ¬rst/early cells - stromatolites"
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