NBB 301 Lecture Notes - Lecture 7: Lipid Bilayer, Membrane Potential, Cockroach

• School: Emory University
• Department: Neuroscience & Behavioral Sci
• Course: NBB 301
• Professor: Frenzel Kristen

Document Summary

Open when membrane potential is more +; but only briefly; keeps opening and closing. Closed when cell at rmp at -70mv or lower. Respond to more + membrane potentials but slower in opening and closing than the. Open -- stable -- high voltage (more likely to be open in high voltage than in low voltage) Closed -- unstable -- low voltage (more likely to be closed in low voltage than in high voltage: channel kinetics, voltage gated k+ a(cid:374)d na+ cha(cid:374)(cid:374)els do(cid:374) t ope(cid:374) at sa(cid:373)e ti(cid:373)e. Both more likely to open at high voltage though: kinetics: probabilistic temporal dynamics of a reaction or mvmt from one state to another. Channels with fast kinetics open and close faster: with slow kinetics; channels are slower/stickier, probability + kinetics + channels --> permeability, refractory period: period or time where we cant easily stimulate another action potential. Absolute : driven by inactivation kinetics of voltage gated na+ channels.