NBB 301 Lecture 9: Lecture 9 readings/videos

• School: Emory University
• Department: Neuroscience & Behavioral Sci
• Course: NBB 301
• Professor: Frenzel Kristen

Document Summary

Khan academy : neurotransmitter release: action potential down axon --> change membrane potential at axon terminal --> open v. g. Electrical: less common but simpler, pores b/w two cells that allow ions to pass through. Ionotropic receptors: also ion channels that open when bound: metabotropic receptors: cascade --> affect gene expression, the presynaptic terminal, nmj: neuromuscular junction: acetylcholine neurotransmitter (anesthetic pathway, epsp: excitatory postsynaptic potential. Ipsp: inhibitory postsynaptic potential: epp: end plate potential. Little blips b/w stimulation = miniature epp (minis) -- also occur in the absence of stimulation --- all roughly same amplitude. This is due to the notion that neurotransmitters are released based on a probability. Amp approximately proportional to ca [] to the 4th power. If ca after stimulation --> no epp (timing mattered: will we see an epp if we directly inject ca++ into presynaptic terminal? yes, drugs. Curare: blocks achr receptors (acetylcholine); used in poison blowdarts: causes the epp curve to disappear completely.