NBB 370 Lecture Notes - Lecture 1: Nathaniel Kleitman, 1918 Flu Pandemic, Atony

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Sleep cycles graph - hypnogram: hypno - sleep, osis - condition, hypnosis - the coming of sleep, artificially induced, how do you know if someone is sleeping, breathing, eye movement, less responsive to stimulus (sensory gating) It"s a reversible state: muscle atonia - lose muscle tone (in rem (rapid eye movement), emg is flat) It"s a cat, so the cerebral cortices are not as folded: enchephale isole - the isolated brain shows eeg signs of alternations among wakefulness, Sleep is a period of reduced activity that is easy to reverse and in which responsiveness to external stimuli decrease. Wake vs sleep: sleep is not the opposite term for wakefulness, as during sleep the brain remains active, although in a different way than wake state. Absence of sleep does not imply wakefulness and vice versa, as different promoting factors are required to achieve each state.

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