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PSYC 210 Lecture Notes - Lecture 18: Striatum, Etiology, Benzodiazepine

34 views7 pages
bluemosquito338
30 Apr 2018
School
Emory University
Department
Psychology
Course
PSYC 210
Professor
Michael Treadway

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Document Summary

The criteria for substance abuse include the following categories: (select all that apply) All drugs of abuse act to increase levels of dopamine in the striatum. Da system becomes super-sensitive to direct effects of drugs and also to drug- associated cues. Sensitivity to drug associated cues (wine bottles, needles, etc. ) Dopamine released to motivate reward to be obtained. Dopamine is most important in motivating behavior to obtain rewarding stimuli. Go to extreme lengths to seek out and obtain drugs. Transition from liking --> wanting maintains addiction, facilitated by da. When seeing particular cues in monkeys, see a large spike in dopamine when seeing juice once you see a triangle. Health animals: overtime begin to associate the cue with the reward. Phasic burst would move to a little before the juice once the triangle is seen. Positive symptoms: inappropriate phasic burst to a neutral object. Negative symptoms: failed response to actual reward cue. Much larger phasic firing compared to the norm.

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