MCB 3020 Lecture Notes - Lecture 34: Lipid Bilayer, Apicomplexan Life Cycle, Rhabdoviridae
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Needed for cysteine, methionine, glutathione, and several coenzymes. Colony forming unit = (# of colonies)(dilution factor)/volume plated onto plate. It will give you a growth curve, but the death phase will not be visible. Nutrition: simple diffusion or ingestion via cytosome, pinocytosis, or phagocytosis. Unicellular; multiple forms including cysts (oocytes), trophozoites, sporozoites, and gametes; frequently intracellular. Protein coat that surrounds the viral genetic material. Consists of single or several different subunits (capsomeres) Two main types of capsids: icosahedral and helical. Capsomers are arranged into equilateral triangles and then 20 triangles come together to form an icosahedron (few proteins --> protomer --> pentamer) Achievable with 60, 180, 240, or 420 capsomeres. *amount of nucleic acid packaged is limited by the size of that particle. Most of these assume a spherical shape except for rhabdovirus (rabies virus) which have a bullet-shaped capsid. *length of the capsid is controlled by the length of the nucleic acid.
