PCB 4594 Lecture Notes - Lecture 7: Hox Gene, Germ Layer, Zinc Finger

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18 Jun 2018
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What can also have a huge influence on the morphology of the organism?
Spatial expression
Syncytium
Only in Drosophila.
Early Embryo.
Divides into one cell.
Eggs develop quickly and in nutrient rich substance.
Changes in embryonic expression pattern of specific hox genes can result in large changes where?
Morphology.
-Chicks have forelimbs and hindlimbs
-Pythons have hindlimbs but no forelimbs
Bicoid
Anterior of embryo
Important for head formation.
Maternally deposited.
mRNA
Nanos
Posterior portion of embryo.
Maternally deposited.
mRNA
What do the Bicoid and Nanos do?
Regulate expression of other developmental genes
Nusslein-Volhard and Weischaus
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