MCB 2000 Lecture Notes - Lecture 6: Propionibacterium Acnes, Staphylococcus Epidermidis, Necrotizing Fasciitis
Document Summary
: microbial diseases of the skin: the largest organ, represents the boundary between the organism and the environment, sometimes shows symptoms of illness not associated with skin (rash. Structure and function of the skin: epidermis. Thin outer part, composed of layers of dead epithelial cells stratum. Connective tissue; hair follicles, sweat glands, oil glands, neurons: sebaceus glands softens and lubricate the skin. Normal microbiota of the skin: normally harmless, able to survive on the skin resistant to drying and high concentration of salt. These microbes cannot be completely removed through cleansing. Those in hair follicles and sweat glands reestablish rapidly responsible for body odor. Representatives: gr+ cocci (staphlycococcus, micrococcus, gr + pleomorphic rods diphteroids; propionibacterium acnes anaerobic bacteria, inhabit hair follicles, produce propionic acid (maintains acidity of the skin ph 3-5, the yeast, malassezia cause skin scaling dandruff. Staphylococcal skin infection: staphylococci spherical gr+ bacteria; form irregular clusters, two groups:
