Class Notes (808,282)
United States (313,040)
Psychology (309)
PSB 2000 (92)


3 Pages
Unlock Document

Florida State University
PSB 2000
Orenda Johnson

Nicotine -Increases dopamine real ease in nucleus accumbens -Stimulates nicotine Ach receptor on VTA neurons and excites -VTA neurons project to NA and releases dopamine -Cells become less responsive after you repeatedly use, the more you use the more the effect decreases (tolerance)-->other pleasures(including nicotine itself) become less reinforcing -You're brain responding to the drugs is trying to do what it can to keep homeostasis Opiates Ex. Morphine, Heroin, Methadone (isn't organic) -Bind to opiod receptors bind to the receptor and have several effects act as neurotransmiand hormones that -Opiates treat pain -Opiods remove GABA inhibition, they are inhibitory they bind to the GABA cells and inhibit the inhibiting GABA cell, more dopamine release -Dopamine release leads to the drug being reinforcing but it's not only doing that but the reinforcing act is happening independently as well -Opiods are also working on the locus coeruleus that makes norepinephrine -Opiods inhibit the nor epinephrin release that decreases stress and memory Methadone (Synthetic Opiod) -Taken to combat an opiod addiction -It is an opiopd receptor agonist, it activates it -Acts somewhat like a nicotine patch -If injected, it doesn't have an effect because they add naloxone -It blocks opiod receptor if injected -The antagonist won't allow the agonist to work -If the pill is taken properly then the stomach will break down the naloxone and only the methadone has an effect -Still dangerous and addicting but more controllable Cannabinoid -Marijuana (delta-THC & other canabinoids) -Smoking this plant activates the CB1 and CB2 metabatropic receptors in your brain -The medulla does not have a lot of canabanoid receptors -When you take other drugs, you can overdoes because there are more receptors for opiods -It's extremely hard to overdose on marijuana -Intense sensory experiences, illusion of time passing slowly, impairment of memory and cognition (hippocampus) -Memory recovers after four weeks without the drug -It causes a neuron to release less of a neurotransmitter, mostly all of them, it decreases their release -Decreases release of GABA allowing more than normal dopamine release -Dissolves in the fats and leaves the body very slowly -Fewer withdrawal systems because it leaves the body slowly -Long term withdrawal systems after long-term use like anxiety, depression, stomach pain, craving, loss of appetite, sleep problems -Most of the time its a reverse effect the withdrawal Alcohol -It is a depressant and inhibits activity in the nervous system -Increases GABA activity everywhere and decreases Glutamate activity the excitatory neurotransmitter so in that sense it is inhibitory and is a depressant -It depresses all of the different regions of your brain like impulse control and socially acceptable behavior, like prefrontal cortex that decreases -Cerebellum is being effected, your balance -GABA and Glutamate receptors are everywhere -The molecules get into the phospholipid bilayer and mess up its function and the cells don't have as much of the selective permeability -There's an action on dopamine receptors, so it is reinforcing, so reinforcing that even though it can make you sick you continue to go back to it -Having an action on opiod receptors, the pleasurable feeling Substance Abuse -Alcoholism is the continued use of alcohol despite medical or social harm even after making a decision to quit -Third largest health problem after h
More Less

Related notes for PSB 2000

Log In


Don't have an account?

Join OneClass

Access over 10 million pages of study
documents for 1.3 million courses.

Sign up

Join to view


By registering, I agree to the Terms and Privacy Policies
Already have an account?
Just a few more details

So we can recommend you notes for your school.

Reset Password

Please enter below the email address you registered with and we will send you a link to reset your password.

Add your courses

Get notes from the top students in your class.