BIOL 120 Lecture Notes - Lecture 14: Lysosome, Monocyte, Cell-Mediated Immunity
Document Summary
Neutrophils, eosinophils, and basophils all contain granules within them that specifically destroy bacteria. How do they know where to go. Cells in tissues are secreting chemicals in the blood and the white blood cells are following the concentration gradient. Can migrate out of the blood stream (diapedisis) Example of this would be mast cells. They do phagocytosis to the marked bacteria. Endosome is fused with lysosome is called a phagolysosomes. There is a lot of free radicals being pumped into this and destroying this bacteria. They take a lot of oxygen (neutrophils) Use the oxygen to make free radicals to destroy the bacteria. Attack and phagocytosis objects coated with antibodies. Responsible for cell mediated immunity, they bind to a specific cell and target it for destruction. They secrete antibodies that bind to specific antigens. They feel sugars on the surface of the body. They are responsible for destruction of cancer cells (natural cancer defense cells)
