CHEM 211 Lecture Notes - Lecture 27: Birch Reduction, Syn And Anti Addition, Reagent

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19 Nov 2016
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Alkenes = contain double bonds: old name = ole ns, ex. vitamin a, cholesterol. Alkynes = contains triple bonds: common name = acetylenes, ex. haloprogin, efavirenz. Physical properties: similar to alkanes, non polar, soluble in non polar substances. Relative stabilities of alkenes: cis and trans do not have the same stability, trans is more stable compared to cis. Cis has more crowding because the big groups are on the same side of the molecule: heat of reaction (heat of hydrogenation) We can tell stability based off the heat of reaction. The higher the energy released, the more unstable. The lower the energy released, the more stable. Overall relative stabilities: tetra-substituted = most stable, un-substituted = least stable, tetra > tri > di > mono > un. For di, the ranking = both on one en>trans>cis. Elimination: two fragments of a molecule are lost from adjacent carbon atoms, multiple bonds created, two kinds e1 and e2.

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