BIOL 3380 Lecture Notes - Lecture 22: Antigen-Presenting Cell, Adaptive Immune System, Dendritic Cell

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4 Jun 2019
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Immunity ability of body to resist or fight off pathogens: antigen toxin or other foreign substance which induces immune reponse in body; substance that is capable of reacting with products of specific immune response, ex. Antibody or specific sensitized t lymphocytes: antibody class of proteins that bind to and inactivate foreign particles like bacteria, viruses, toxins, etc. Innate (non antigen specific: barriers and defense, anatomical barriers, ex. Inhibit complement components: s. aureus scin inhibits c3 convertase, how does innate immune system identify pathogens, all multicellular organisms are able to recognize and eliminate pathogens, despite heterogeneity, pathogens share highly conserved molecules called. Pathogen associated molecular patterns (pamps: host cells do not share pamps with pathogens, pamps are recognizes by innate immune recognition receptors called pattern recognition molecules / receptors (prms, prrs, typical pamps, bacteria, lipopolysaccharide, peptidoglycan, flagellin, lipotechoic acid, Adaptive (antigen specific: characteristics, yesinia pestis modifies lps to limit detection by host cells.

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