PSYC 372 Lecture Notes - Lecture 5: Prefrontal Cortex, Perseveration, Clive Wearing

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Learning: acquiring new info memory: persistence of learning in a state that can be revealed at a later time; memory is the usual consequence of learning. Relearning was proportional to extent of cortical lesion and not location. Delayed matching to sample (monkeys) amnesia: failure of memory processes. Retrograde: trauma in present inhibits retrieval of memory before trauma. Anterograde: trauma in present inhibits learning and retaining new info after trauma. Squire model of memory amnesia syndrome can be produced by damage to several structures. Subcortical (diencephalon): specifically the dorsomedial thalamus patient hm and medial temporal lobe amnesia. Removed of the hippocampus, some of surrounding cortex, amygdala. Severe global amnesia: could not recognize amnesia, laughed at same jokes, read same newspapers assessment of hm. Fail on traditional tests of memory: recognition and recall. These tap into declarative memory (episodic and semantic) Can draw upon episodic memory or knowledge of the world depending on task. Stm is intact; he can rehearse unless distracted.

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