BIOL 2107K Lecture 11: Chapter 10 Notes Cell communication
Document Summary
Cells: maintained by cytoskeleton, adhere via extracellular matrix, communicate via cellular junctions. Epithelial cells lining inside and out. Ecm basal lamina - support: cushioning dermis nutrients, hydration. Anchorage for organelles and enzymes in cytosol. Microfilaments- a double helix of actin monomers. Microtubules- hollow tube formed from tubulin diners. Intermediate filaments- a strong fiber composed of intermediate filament proteins. Core of the microtubules encased in plasma membrane. 9+2 pattern- nine doublets arranged in a ring surrounding 2 single microtubules: anchored within cell to basal body, similar to centriole. Motor molecules- dynein protein- dynein walking along microtubule. Separates cytosol into gel-like and fluid like regions: muscle contraction, amoeboid movement, cytoplasmic streaming. Moves with pseudopod, pulls one part ahead then rest of body catches up. Often play a role in cellular junctions. If lost, then no strength , leading to tears. Keratinocytes provide the structural support of skin- example. Dynamic growth and instabilities of microtubules and microfilaments.