NURS 2060 Lecture Notes - Lecture 1: Urinary System, Tubular Fluid, Hypotension
Document Summary
Compare strong acids to weak acids when describing their ability to dissociate: strong acids dissociate completely. Describe how acidosis can lead to potassium retention: k+ and h+ ions work in opposites, in hypokalemia, an intracellular acidosis can develop; in hyperkalemia, an intracellular alkalosis can develop. List the 3 sources for hydrogen ions in the body: carbonic acid formation, inorganic acids produced during breakdown of nutrients (sulfuric acid from eating steak, organic acids resulting from intermediary metabolism (fatty and lactic acids) Loss of hcl due to vomiting: proteins. Excellent buffers because they contain both acidic and basic groups that can give up or take up h: hemoglobin. Most of the h+ generated from co2 at the tissue level becomes bound to hemoglobin (hb) (happens in the rbc: phosphate. Important intracellularly as well as in the urine. In order for h+ ions to continue to move from renal cells into urine the free h+ levels must be low.
