PHYL 141 Lecture Notes - Lecture 6: Haematopoiesis, Hip Fracture, Fibroblast

• School: UH, UH Manoa, UHM
• Department: Physiology
• Course: PHYL 141
• Professor: Rachel Lindsey

Document Summary

Bone tissue - complex & dynamic living tissue that continually engages in bone remodeling. Bone remodeling process of building new bone tissue & breaking down old bone tissue. Bone organ made up of several different tissues working together bone (osseous tissue), cartilage, dense connective tissue, epithelium, adipose tissue & nervous tissue. Skeletal system entire framework of bones & cartilages. Long bone is covered by articular cartilage at articular surfaces of its proximal & distal epiphyses, and by periosteum around all other parts of the bone. Initiated by osteoblasts, bone-building cells: bone"s hardness depends on crystallized inorganic mineral salts, bone"s flexibility depends on its collagen fibers, collagen fibers & other organic molecules provide tensile strength (resistance to being stretched/torn apart) **osteoblasts build bone, whereas osteoclasts carve out bone** Two types of bone tissue: (1) compact bone = 80% of skeleton & (2) spongy bone = 20% of skeleton. Contains fingerlike processes of osteocytes & neighboring osteocytes communicate via gap junctions.