BIO E105 Lecture Notes - Lecture 11: Post-Translational Modification, Start Codon, Peptide Bond
Document Summary
The ribosome moves ahead three bases and all three trnas move down one position; the. The ribosome is a molecular machine that synthesizes proteins in a three-step sequence. An trna carrying the correct anticodon for the mrna codon enters the a site. A peptide bond forms between the amino acid on the trna in the a site and the growing polypeptide on the trna in the p site. trna in the e site exits. Translation has three phases: initiation, elongation, and termination. The initiation phase of translation begins at the aug start codon. The interaction between the small subunit and the mrna is mediated by initiation factors. At the start of the elongation phase, the initiator trna is in the p site, and the e and a sites are empty. An trna binds to the codon in the a site via complementary base pairing between anticodon and codon.
