BIO E105 Lecture Notes - Lecture 16: Cystic Fibrosis, Missense Mutation, Reading Frame
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In some cases, there is not a clear dominance relationship among alleles: Co-dominance: the example of blood types (equal impact on phenotype) Incomplete dominance: flower color (blending on protein products) Cystic fibrosis (cf) is an autosomal, recessive genetic disorder. Characterized by abnormal transport of sodium and chloride silent = no change nonsense = premature stop missense = alters structure frameshift = change in reading frame. Huntington"s disease is genetically dominant; caused by mutation of htt (huntington) genes. So how do mendel"s experiments (see the reading for this section) revealed the properties of: > in biology, structure has a profound influence on function. Biologists analyze the structure and function of animals at a variety of levels: molecules, cells, tissues, organs, and organ systems. > body size has a strong influence on how animals work, in large part because a body"s volume increases faster than its surface area as body size increases.
