AN S 345 Lecture Notes - Lecture 19: Lysine, Lipopolysaccharide, Histidine
16 Mar 2017
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Document Summary
Tells the cell to initiate protein synthesis. This is a kinase - which allows the proteins to change function ; by changing shape activated by phosphorylation. Regulated by anabolic growth factors and nutrients. Kinase sits in the cell and waits for a stimulus. A callipyge [cal-pee-j] lamb, more nuclei to muscle fibers, has growth factors binding to receptors on cells. First there is a positive energy balance and as a result there is a phosphorylation of mtor. Third activation of the kinase causes a shape change in the protein which. This whole process is protein synthesis initiation at a cellular level results in a change in function. The sheep on the left is double muscled and the sheep on the right is not. The double muscling will yield a larger meat cut. Nutrients aid in protein synthesis by speeding up translation. Lysine, histidine and thiamine can have negative impacts on protein synthesis via mtor.
