PSYC 3 Lecture Notes - Lecture 21: Cholecystokinin, Psych, Ventricular System
21 Sep 2020
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Ghrelin is a peptide hormone released by the stomach that increases eating. Blood levels of ghrelin increase with fasting and are reduced after a meal increasing food intake and decreasing the metabolism of fats. Administering ghrelin into the cerebral ventricles cause weight gain by. Schmid et al. (2005) found that a single intravenous injection of ghrelin not only enhanced appetite in normal subjects it also elicited vivid images of foods that the subjects liked to eat. A fall in blood glucose level (a condition known as hypoglycemia) is a potent stimulus for hunger. Hypoglycemia can be produced experimentally by giving an animal a large injection of insulin which causes cells in the liver, muscles, and adipose tissue to take up glucose and store it away. A dramatic fall in the level of glucose (checking account) available to cells. A dramatic fall in level of fatty acids (savings account) available to cells. Lose savings account (not immediate effect) stimulates hunger.
