PSYC 3 Lecture Notes - Lecture 24: Dihydrotestosterone, Fallopian Tube, Vas Deferens

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Early in development have precursors for both m and f internal sex organs. At approximately 12 weeks one system develops and the other withers away. The gender of the internal sex organs is determined by the presence or absence of hormones secreted by the testes. If no hormonal stimulation (no testes) then mullerian system develops. If there are testes present they release: Wolffian system contains androgen receptors that are coupled to cellular mechanisms that promote growth and division. In absence of hormones the external genitalia become f. In the presence of d-ht they become m. Androgen insensitivity syndrome congenital lack of functioning androgen receptor. Cause: mutation that prevents formation of functioning androgen receptors. These individuals are (gener for androgen receptor is on x chromosome) Testes release anti-mullerian hormone, t, and d-ht. Anti-mullerian hormone still defeminizes so there wont even be female internal organs developed. Cant respond to t so no masculinization.

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