BSCI 10001 Lecture 14: Cell Division

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Lets take a closer look at the replication of the bacterial dna molecule: While prokaryotes have a single, circular dna molecule as their chromosome, a eukaryotic cell typically has multiple chromosomes, each of which is a long, linear dna molecule. Each of these linear molecules has multiple origin sites, at regular intervals. Prokaryotes replicate their dna continuously when they are growing. Since dna replication can occur at a faster rate than cell division, rapidly growing bacteria often have multiple copies of replicated dna per cell. But eukaryotic cells replicate their dna only once before each cell division, and they do this during a discrete period of their growth cycle. This discrete period of dna synthesis is called the s-phase ( s stands for synthesis, ie, dna synthesis). Eventually, it came to be understood that chromosomes contain the genetic material (dna), and that prior to mitosis (sometime during interphase) the dna is replicated.

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