CO SCI 136 Lecture Notes - Lecture 20: Chemical Bond, Sildenafil, Paracetamol
Document Summary
Pharmacology: science of drugs (mechanism of action, how effects can be measured, their discovery, design n development, action on org. n action of org. on them) Therapeutics: medicinal use of drugs to treat / relief symptoms of disease. Pharmacy: how drugs are formulated and dispensed for use as medicines (include law governing medical use of drugs) Toxicology: focuses on harmful effect of chemicals (drugs) Drug: chemical substance of known structure that produce biological effect when used (except nutrient/essential dietary ingredient) How are drugs named: chemical name, common name *expect to know, proprietary (trade) name. Grouped by therapeutic use / mechanism of action (e. g. ibuprofen is a cyclooxygenase inhibitor that acts as an analgesic) 5-[2-ethoxy-5-(4- methylpiperazin-1- ylsulfonyl)phenyl]-1- methyl-3- propyl-1,6-dihydro-7h- pyrazolo[4,3-d]pyrimidin-7-one ( )-4-[1 hydroxy-4-[4- (hydroxydiphenylmethyl)-1- piperidinyl]-butyl]- , -dimethyl benzeneacetic acid hydrochloride short-acting 2 adrenergic receptor agonist phosphodiesterase type 5 (pde5) inhibitor selectively peripheral h1- blocker. Inderal tremors, angina (chest pain), hypertension (high blood pressure), heart rhythm disorders.
