ELECTRN 8 Lecture Notes - Lecture 2: Pulse Oximetry, Caloric Reflex Test, Basilar Skull Fracture
Document Summary
Andriessen clinical characteristics and pathophysiological mechanisms of focal and diffuse. Tbi = most frequent neurological disorder worldwide: leads to reduced quality of life and vast socioeconomic costs. Tbi is a dynamic process results in alterations in function and structure of all elements of the brain. Review aim: overview of clinical consequences of tbi and current concepts of pathological processes underlying damage of nerve cells and axons. Motor score is strongest predictor in terms of survival. Essential factor in development of shear strain = direction of head movement: lateral head movement associated with more severe diffuse damage than sagittal head movement. Both types of injury could result in coma, vegetative state or pta, however recovery appears less predictable after focal than diffuse tbi. Support: after diffuse injury, and not focal injury, duration of unconsciousness and pta strongly correlated with functional outcome at 6 and 12 months: forth stage: characterized by diversity of cognitive, behavioral, mood and sensorimotor disturbances.
