ELECTRN 8 Lecture 3:
Document Summary
Persistent increases in synaptic strength (biological substrate for learning and memory) Mg2+ is not removed: but, still low level of calcium flow into the post- synapse, activates distinct protein kinases: calcineurin. Ltd prevents ltp saturation & even increase its effects. Ltd limits the degree of excitation & eliminates unnecessary circuits. Stronger synapses = post-synaptic cell is more sensitive to glutamate & greater glutamate release. Ltp maintenance (e. g. postsynaptic density proteins & synaptic proteins supports structural changes (e. g. dendritic enlargement. Resistance exercise = production of force under low repetition and predominantly recruit anaerobic respiration stimulate skeletal muscle growth & strength adaptation is myo-centric. Aim: chapter focuses on acute & chronic adaptations resulting from exposure to aerobic exercise. Methods: two classifications of experimental exercise in rodents. Relies on use of motorized treadmill or wheel to. Advantages allows greater experimental control (intensity, duration, metabolic rate, etc. ) assess both acute & chronic paradigms measuring improvements in performance.
