BIOL 1201 Lecture Notes - Lecture 1: Endergonic Reaction, Thermodynamics, Atmospheric Circulation

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13 Jan 2017
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Chemical reactions: when two or more atoms, ions, or molecules collide in such a way that they produce a new substance. Energy can neither be created nor destroyed only converted from one form to another: 2nd. When converting energy from one form to another the amount of useful energy decreases. Spontaneous reaction release free energy (exergonic: g= - Non-spontaneous - require free energy (endergonic): g= + Change in free energy: g= free energy, h=enthalpy, t= temperature, s= entropy, g = h -t s. Enthalpy decreases, entropy increases: non spontaneous = enthalpy increase, entropy decrease. Enthalpy decreases; entropy increases: lighting the match heat energy is released. Inhibitor binds to the active site + blocks access to the active site: noncompetitive inhibition: Inhibitor binds to a site other than the active site + alters the shape of the active site: allosteric inhibition/ regulation: Enzymes alters b/w active + inactive forms. Allosteric (cid:862)other shape(cid:863), (cid:272)hanges shape (cid:271)y itself.

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