BIOL 1201 Lecture Notes - Lecture 1: Rotenone, Citric Acid Cycle, Atp Synthase

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29 Jan 2018
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To continue to pump hydrogen ions there must be a continuous flow of electrons along the etc. Uses the exergonic flow of electrons from food (glucose) to oxygen to drive the endergonic synthesis of atp. Adds phosphate group to make adp to atp. Direct transfer of a phosphate group to adp from an organic molecules with a high energy phosphate bond. Comes from taking it off the organic median. Once a cell is completely out of atp, it can t do this. Bears have a tissue known as brown fat. In these cells the mitochondria have a special protein known as thermogenin. This is a facilitated diffusion channel for h+, with no associated atp catalytic site. Rotenone is a widely used pesticide and fish poison. It prevents the transfer of electrons from the 2nd and to the 3rd molecules in the etc. Cells need more energy than what is allowed. Fermentation: an alternative to most of this pathway.

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