BIOL 2153 Lecture Notes - Lecture 1: Yoda, Muller'S Morphs, Wild Type

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They are different genes, encoding different proteins, but they do not assort independently. Hla-a, hla-b, and hla-dr alleles almost always inherited together as a haplotype. If yellow is simply dominant, crossing two yellows we expect of the cross to be gray: one good allele is enough to get through development in the yellow mice, polydactyly in humans. In pedigree iii-2 is not affected but had the trait without expressing it. If it"s a dominant trait and someone doesn"t express it but child does, then it is incomplete penetrance. Lobe in drosophila: variable expressivity, the phenotype is variable, genotype and environment affect phenotype, genotype is not the only factor affecting phenotype, environmental effects on phenotype, pku is a neurological effect that has a very simple genetic basis. A prefix means not, so think no function: hypomorph reduced function of gene product. Hypo means under, so think reduced function: can have different types of function.

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