BIOL 3156 Lecture 4: Week 4 (aced the test and got 96%)
Document Summary
Hnk1 an ncc marker protein, make the orange cells. Ncc"s really do only show up in the anterior portion of the sclerotome. The do not go into the posterior at all. Transplant ncc into embryos of different developmental stages. Use somite number as marker for where the ncc"s come from. Transplant to young vs old embryos : young no migrations of trunk ncc"s have occurred, old one of two ventrolateral migrations have taken place the one that goes deepest ventral occurs first. So old cells already took care of second pathway and young ncc"s don"t need to, according to the cells. Labeled cells from young donor to old host: labeled cells in 2nd wave only!! Results show that cells are multipotential and are differentiated at final resting point. In all cases, as development continues, fate of a cell becomes more and more channeled until it finally becomes a differentiated cell.
