BIOL 4087 Lecture Notes - Lecture 14: Adipose Tissue, Allosteric Regulation, Transmembrane Protein

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7 Dec 2017
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Increased levels of nadh feedback negatively into citric acid cycle by allosterically inhibiting pyruvate dehydrogenase, citrate synthase, and (cid:417)-ketoglutarate decreases production of nadh and thus decrease production of. 2 of 7: complex i: nadh dehydrogenase, transfers the electrons from nadh to coenzyme q or ubiquinone (named because it is ubiquitous in respiring organisms), nadh is oxidized while the complex i is reduced. 3 of 7: the h+ flow back into the matrix through a pore associated with the enzyme atp synthase provides the only place to relieve this electrochemical and concentration gradient. Thus, h+ ions will flow spontaneously through the inner mitochondrial membrane from the intermembrane space into the matrix: atp synthase has two different types of subunits. Intermembrane space: f1 subunit (located in inner mitochondrial membrane, contains five different subunits and protrudes into the mitochondrial matrix. It also has the catalytic activity site of the enzyme.

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