KIN 3515 Lecture : KIN 3515 Lecture 4 09 03 15

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If you want more force, you form more cross-bridges. Two ways to get more sarcomeres: hypertrophy-this means is to increase number of myofibrils in muscle cell. Myofibril is a tube of sarcomeres end to end. more cross-bridges, the more force you can exert: hyperplasia-increase number of cells in the muscle, reverse is called atrophy where you lose cells. In humans there is controversy on whether hyperplasia can occur. They take a muscle biopsy and use a very small needle: hyperplasia has never been proven in humans but has never been disproven. Has been proven in most other animals: one study was done on young twins that died around age 20, muscles aren"t the same size as when you were born. Muscles got bigger and size of the cell. As you develop into fetal stages, these cells fuse together and make multinucleated muscle cell.

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