PSYC 2000 Lecture Notes - Lecture 28: Acetyl-Coa, Citric Acid Cycle, Intermembrane Space

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Glucose metabolism: c6h12o6 + o2 6co2 +h2o + energy. Electron transport chain - inner mitochondrial membrane. Nadh and fadh2 give off electrons to etc and become nad+ and fad. If o2 were no longer present, electrons would build up and atp would not be made. Each nadh pumps enough h+ into intermembrane space to phosphorylate 3 atps. Each fadh2 pumps enough h+ into intermembrane space to phosphorylate 2 atps. Atp , fadh2, nadh least energy to most energy. Cytoplasm - glycolysis - glucose lysed into 2 pyruvates - net yield= 2 atp. Mitochondrial matrix -acetyl coa and krebs cycle or citric acid cycle. 10 nadh, 2 fadh2, 6 co2 expelled as waste, 2 atp. Inner membrane - etc - o2 - water and 32 atp. Cyanide stops flow of electrons to o2. Carbon monoxide - co, directly interferes w flow of electrons. Fe, iron is what cn, oo, and co bind to.

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