BIOL 130 Lecture Notes - Lecture 14: Acetyl-Coa, Oxidative Phosphorylation, Intermembrane Space

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28 Nov 2016

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Acetyl coa- 2 carbon group added to the four. Product of oxaloacetate + acetyl coa= citric acid. Decarboxylation- remove carbon dioxide- steal electrons and put them into nadh. Dehydrogenation- forms fadh2 (lose hydrogens) occurs in citric acid cycle! Citric acid cycle must run twice because per one glucose=2 fadh2 and 6 nadh. Glycolysis, pyruvate oxidation, and the citric acid cycle has completely oxidized each carbon in glucose. The 24 electrons in the c-c and c-h bonds have been transferred to 10 nadh and 2fadh2. Objective- describe the work that is preformed when energy is removed from the electrons. Electrons keep bouncing until they get to oxidation because otherwise we would combust. Some energy is lost in this, but the lost energy is used in active transport of the protons. Objective- illustrate conversion of energy of the h gradient is transformed into atp (chemiosmosis)

Related Questions

Which of the following is not a net product of the citric acid cycle for each molecule of pyruvate generated in glycolysis?

Select one:

a. 1 ATP (GTP)

b. 1 acetyl coA

c. 3 NADH

d. 1 FADH2

Question 2

Which of the following is NOT an end product for an acetyl group that enters the citric acid cycle?

Select one:

a. ATP

b. NADH

c. FADH2

d. oxaloacetate

Question 3

Once they have been processed through the citric acid cycle, the acetyl-CoA molecules from a single glucose molecule produce:

Select one:

a. 2 ATP, 6 NADH, 4 CO₂.

b. 6 NADH, 6 GTP.

c. 6 FADH₂, 2 ATP, 6 CO₂.

d. 6 GTP, 6 FADH₂.

e. 4 CO₂, 6 FADH₂, 2 ATP.

Question 4

The products of the citric acid cycle breaking down 2 acetyl-CoA include 2 ATP (converted from GTP), 6 NADH and 2 FADH2.

Select one:

True

False

___ 25- The Krebs cycle begins with the union of acetyl CoA with oxaloacetate forming citrate, allowing oxidative decarboxylation reactions to occur, and ends with the conversion of malate to oxaloacetate. Using this information and your knowledge of the Krebs cycle, how many net carbons does the citric acid cycle gain?
A) 0 carbons
B) 1 carbon
C) 2 carbons
D) 4 carbons
___ 26- Directly from the Krebs cycle we can obtain:
A) ATP
B) GTP and NADPH
C) ATP and NADPH
D) ATP, GTP, and NADPH
___ 27- Which of the following is not an intermediary of the Krebs cycle?
A) oxaloacetate
B) citrate
C) succinyl CoA
D) acetyl CoA
___ 28- How many di nucleotides are reduced by four turns of the Krebs cycle?
A) 1 FADH2 and 4 NADH
B) 2 FADH2 and 8 NADH
C) 4 FADH2 and 12 NADH
D) 1 FAD and 4 NAD +

The reduced nucleotides NADH and FADH are converted to ATP via the electron transport chain and oxidative phosphorylation. The most widely accepted values among biochemists are shown.

Nucleotide Output	ATP Output
NADH	2.5
FADH₂	1.5

Each acetyl CoA entering the citric acid cycle produces two CO₂, three NADH, one FADH₂, and one GTP (converted directly to ATP in the cell). Taking into consideration the conversion of reduced nucleotides to ATP, what is the total number of ATP produced by one glucose (2 Acteyl CoA) going through the citric acid cycle?

BIOL 130 Lecture Notes - Lecture 14: Acetyl-Coa, Oxidative Phosphorylation, Intermembrane Space

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